Hello Tobie,
Yes, you can use the simulation method for one area and the prescriptive method for another. Document both methods as you would if you were doing them individually. It might be helpful to note on the plans "See prescriptive method for this area." Then, just submit some sort of summary table that lists the area that complies (an all or none for your prescriptive method spaces and the actual portion for your simulated areas). Take this divided by the total ROS and if that % is over 75, you have achieved one point, over 90 is two points.
Is that what you were asking?