Some rules of thumb to reduce energy use are:

Program similar spaces together to reduce distribution losses 
Use a window-to-wall ratio below 40%, on average
Use a window-to-wall ratio below 20% on east and west sides, to reduce low-angle solar gain, and glare; 
Reduce direct solar gain with solar shades or building geometry and orientation
Distribute heating and cooling loads uniformly throughout all facades for a smaller system size. 
Design a tight and well-insulated building envelope to reduce the heating load and improve HVAC performance
Use right-sized and efficient heating and cooling systems
Consider onsite renewable energy generation.