The mechanical engineer and architect review ASHRAE-55 along with the credit requirements in the context of the project. ASHRAE-55 requires that you establish a comfort zone based on several variables that affect occupant comfort, and design mechanical systems to create thermal conditions within the comfort zone in each occupied space. Comfort zone calculations are based on the following variables:

Metabolic rate
Clothing insulation level
Air temperature
Radiant temperature
Air speed
Humidity