How do you deal with exception (b) to G3.1.1?

Do you apply a single-zone system (1) to spaces that have a COOLING or HEATING PEAK LOADS that differ more than 31.2 W/m2 to other spaces served by the main system (what I mean for "peak thermal loads" referred by the standard), OR (2) to spaces that have PROCESS LOADS that differ more than 31.2 W/m2 to other spaces served by the main system (unregulated load, that is the literal meaning of "process loads" even referred by the stadard a few lines before)?

I've noticed some relevant consequences:

- if (a) you do not know it before sizing runs, and with the 4 rotations you can have different single-zone system spaces for each rotation (and therefore issues in filling data in Air-side HVAC sheet of the MEPC - Minimum Energy Performance Calculator)

- if (b) you know it before sizing runs and you have the same systems configurations for all the 4 baseline rotations, but the evaluation is limited to cooling baseline design, and what about Occupancy and Lights, other fixed (=not varying with rotation) internal gain that produce cooling loads too?

Thank you for any insight 

Alessandro