Clean Room Protocol and SMACNA standards

We are currently working on a LEED project where a significant portion of the finished space will classify as “Clean Room” under ISO 14644-1. It is our understanding that Clean Room standards are much more rigorous than SMACNA standards; however, we don’t have any previous experience with Clean Room requirements. With our limited experience in this area, we don’t want to prompt action on the part of the contractor (& Subs) to fulfill LEED requirements that will conflict with Clean Room and ISO 14644-1 requirement. Does anyone have any experience working on a LEED project which included Clean Rooms? If so, how do the standards compare?